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Standardized, reproducible animal and ex vivo models that reflect polymicrobial niches, immune interactions, and clinically relevant exposure to anti-biofilm agents will enable the testing of adjunctive strategies against biofilm development prior to transitioning to clinical practice (Nett et al., 2010

This process removes water from the peptide solution while preserving its molecular structure, resulting in a stable powder that can be stored for extended periods

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In parallel, increasing emphasis on regulated and reproducible synthesis strategies aims to reduce batch-to-batch variability, and improve biological evaluation dependability [91, 103]