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Was the result independently replicated

Its essential to differentiate between self-initiated changes (where the individual decides to modify their own routine) versus externally imposed changes (those that are unexpected or forced upon them)

It is important to note that although no specific studies have been performed on synovial myofibroblasts in OA, integrins containing the v-, 5-, and 1-subunit are increased in the synovial lining layer in OA (72)

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