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The human CHAC2 protein consists of 184 amino acids, has a molecular weight of approximately 20.9 kDa, and is encoded on chromosome 2p16.2 (Kaur et al., 2017

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In the process of purine synthesis, 5-phosphoribosyl--pyrophosphate (PRPP) generated from the pentose phosphate pathway (PPP) is converted to phosphoribosyl--amine (PRA) through the action of phosphoribosyl pyrophosphate amidotransferase (PPAT) when an amide group from glutamine is introduced

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