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Studies point towards a significant role for excess iron in driving key pathological processes of the disease

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(2020) Prescribing and Consumption of Opioids After Primary, Unilateral Total Hip and Knee Arthroplasty in Opioid-Nave Patients

As far as the intracellular Cu(I) discharge pathways are concerned, Cys containing small peptides, such as GSH, or the antioxidant peptide Atox1 may contribute to Cu(I) release from the carrier