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Preoperative Preparation: To stabilize patients before thyroid surgery or radioactive iodine therapy

In more recent studies, serum vitamin E levels were predictive of hemorrhagic events, especially in vitamin K-deficient patients (one interventional study on 12 cardiology patients receiving long-term warfarin, with mild-to-moderate prothrombin times (range, 16.021.5 s), and one retrospective observational study on 566 consecutive patients) [305,306] (Table 2)

Studies in cultured hepatocytes and in vivo

Infected mice exhibit characteristic anxiety and depressive-like behaviors correlated with reduced antioxidant enzymes (SOD, GSH) and elevated malondialdehyde (MDA) levels, indicating ROS-mediated lipid peroxidation