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Furthermore, selective inhibition of -glutamylcysteine synthetase (which results in glutathione depletion) in the alveolar perinatal epithelium abrogated hypoxia-induced nuclear localization, stabilization and activation of HIF-1 [13, 14]

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Anna Growe (Kassel University) 641 Strategic metropolitan governance for resilience in practice: The Barcelona Metropolitan Commitment 2030 and the governance model in the German Metropolitan Region Rhein-Neckar The Metropolitan Commitment 2030 is a strategic framework led by the Metropolitan Strategic Plan of Barcelona (PEMB) which aims to create a more sustainable, equitable, and resilient metropolitan region by 2030, aligning with global objectives such as the United Nations' Sustainable Development Goals (SDGs)