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Because AOD9604 does not stimulate IGF-1 production and lacks strong GH receptor agonism, it may present a safer alternative for long-term OA treatment [1]

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BPC-157, short for Body Protection Compound-157, is a stable pentadecapeptide consisting of 15 amino acids

It is released from the extracellular matrix during tissue injury specifically cleaved from SPARC (Secreted Protein Acidic and Rich in Cysteine) and the alpha 2(I) chain of type I collagen.[2] Age-related decline: Plasma concentration declines from approximately 200 ng/mL (10 M) at age 20 to roughly 80 ng/mL by age 60