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For example, using peptides together with medicines metabolized by cytochrome P450 can lead to increased levels of these medicines in the blood, which may raise the risk of side effects
Gao F, Chen J, Ma T, Li H, Wang N, Li Z, Zhang Z, Zhou Y (2014) The glutathione peroxidase gene family in Thellungiella salsuginea: genome-wide identification, classification, and gene and protein expression analysis under stress conditions
169 (1): 132147.e16
However, studies in women reveal no effect on GH or prolactin, showing its hormonal influence is selective and varies by context
In summary, arginine depletion may be a feasible approach for cancer treatment because of the anti-cancer effects reported in pre-clinical studies, the low adverse reactions and the treatment-achieved stable disease in clinical trials of advanced stage cancers
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