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Excessive activation of TLR signaling could be harmful and lead to tissue injury, including chronic inflammation and autoimmune diseases [262]

Higher fibroblast density at the repair site correlates with faster structural closure of tendon defects in preclinical histology

In another in vivo study, 6-gingerol in phosphate-buffered saline reduced IL-17 infiltration from the peripheral blood into the central nervous system, as well as neuroinflammation and demyelination (Han et al., 2019