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Peer review Peer review information Nature Reviews Molecular Cell Biology thanks Fudi Wang, Jos Pedro Friedmann Angeli and Qitao Ran for their contribution to the peer review of this work

Combination with other therapies produces best outcomes

Gastric-Derived Tissue Healing Peptide BPC-157 is a stable, synthetic 15-amino acid peptide derived from a naturally occurring protein found in human gastric juice

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Real-time PCR analysis indicated an initial downregulation of C4 , C4A , and MBL , followed by an upregulation of CD93 , C1q , C1s , C3 , C3AR1 , C5AR1 , and C6 over time