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Furthermore, hitherto puzzling observations, such as the halo formation in complementation experiments carried out with arGST-deficient maize and Arabidopsis plants 28 , and the requirement for arGSTs in proanthocyanidin formation in planta 27 , can be rationalized with the catalytic role of arGSTs in producing anthocyanidin precursors

101 : 539547 Fulda S, Susin SA, Kroemer G, Debatin KM and (1998) Molecular ordering of apoptosis induced by anticancer drugs in neuroblastoma cells

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While these can provide localized antioxidant support, they often struggle to penetrate deep enough into the dermis to influence pigment production at the cellular level