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1 2 3 American Family Physician

[DOI] [PMC free article] [PubMed] [Google Scholar] 28.Slavich G.M., Mengelkoch S., Cole S.W

The rat research suggests that acetyl-L-carnitine plays a role in the brain, preventing the excessive firing of excitatory neurons, but this will need to be explored further as well

Although skeletal muscle can tolerate this metabolic shift, consequences for brain function could be devastating due to the heavy reliance on mitochondrial oxidative phosphorylation for generating energy needed for cellular processes

Melatonin Enhanced Microglia M2 Polarization in Rat Model of Neuro-inflammation Via Regulating ER Stress/PPAR/SIRT1 Signaling Axis