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In addition, menthol has been shown to be an allosteric inhibitor of alpha 7 type nAChR (Ashoor et al., 2013), which are densely located in the hippocampus and the prefrontal cortex and modulate a broad range of cognitive functions (Tregellas & Wylie, 2019)

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Transient receptor potential vanilloid type-4 (TRPV4) is a Ca 2+ -permeable cation channel that has been implicated in inflammatory diseases (198)