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It also systematically reviews the current literature about e-cigarettes and heated tobacco products

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Smokeless tobacco products like chewing tobacco and snuff present their own risks, including oral cancers, gum disease, and cardiovascular complications

Cigarettes must burn in order to be smoked, and the tip of a cigarette can reach hundreds of degrees Celsius when lit

Essentially, this device uses specially designed tobacco sticks called 'TEREA' that are inserted into the heating chamber of the IQOS pen, also referred to as the 'holder'