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The induction of the NADPH oxidase (NOX) system by proinflammatory mediators can generate BBB permeability by downregulation of proteins involved in intercellular junctions such as VE-cadherin, occludin, and claudin-5 (Rochfort et al., 2014)

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Allow 15 days minimum between cycles for blends to prevent receptor desensitization

These hours must be completed under the supervision of a licensed PT and can be volunteer hours or paid hours through a rehab aid/tech position

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