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The long-term exposure of -cells to IL-1 and IL-6 may lead to apoptosis, resulting in insulin resistance and increased glucose levels in the blood [37]

These rafts may facilitate the colocalization of APP with its cleaving enzymes, enhance the activities of and secretases, and influence the endocytosis of APP, thereby mediating its amyloidogenic pathway

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N-Acetylcysteine (NAC) in schizophrenia resistant to clozapine: A double-blind, randomized, placebo-controlled trial targeting negative symptoms

COSMAX provides a structured environment where these different elements can be managed within a single development pipeline