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Agronomy 11:547

Sharan N, Chong VZ, Nair VD, Mishra RK, Hayes RJ, Gardner EL: Cocaine treatment increases expression of a 40 kDa catecholamine-regulated protein in discrete brain regions

And I know this reads like geek speak and may have you feeling like you ARE back in senior year chem class, so let me explain it with an Iron Man analogy

In the absence of SIRT4, a failure to undergo cell cycle arrest induced by DNA damage causes a delay in DNA repair and increased chromosomal instability, suggesting a tumor suppressor effect of SIRT4 151

PARPs are most commonly known for DNA repair, although they also function in transcription, cell cycle regulation, and proteasome regulation 7