Because their association has been investigated in cohort studies, this doesnt necessarily mean that high TMAO levels actually cause these conditions
The relevance of arginine metabolism in DCs is further highlighted by the identification of a specific DCs subpopulation that is characterized by TNF- and NOS2 expression, hence known as TNF-, iNOS-producing DCs (Tip-DCs) (35, 36) Tip-DCs exert pro-inflammatory roles conferring resistance to Listeria monocytogenes , Brucella melitensis , and Leishmania major infections (3638)
E.Jr.SantiniR.Jr.Perez-SantiagoE
Thank I'm Andrew Huberman, and I'm a professor of neurobiology and ophthalmology at Stanford School of Medicine
Following this characterization, the organoids were dissociated, and the enriched AEC2 cells were seeded onto an OoC system, enabling their application in a microfluidic environment