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The result is a synergistic pulse that is significantly larger than either peptide alone, while still being a physiological pulse rather than a pharmacological spike

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( (Electronic) ) Palls M et al (2009) Resveratrol and neurodegenerative diseases: activation of Sirt1 as the potential pathway towards neuroprotection

This release of secondary messenger molecules, such as IP3, might potentially stimulate the discharge of calcium ions (Ca2+) from the cells internal stores