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Although these therapies are often discussed together, they work through very different biological pathways

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They are involved in a variety of intracellular events, such as primary and secondary metabolisms, stress metabolism, herbicide detoxification and plant protection against ozone damage, heavy metals, seedling development

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While agonist peptides based on either scaffold are potent in rat obesity models 2,10,11,12,13 , only a transient weight loss effect is observed with sCT in mouse diet-induced obesity (DIO) models 14 , indicating that there may be distinctions in the mode of action of individual dual agonists