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However, Keap1 KD mice did not develop any spontaneous cancers

It may be clustered into three enterotypes according to the species composition and functional properties

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Mathiesen DS, Bagger JI, Bergmann NC, Lund A, Christensen MB, Vilsboll T, et al

10.1002/dmrr.3173 Summary Keywords AMPK, anthracycline cardiotoxicity, autophagy, cardioprotection, diabetic cardiomyopathy, heart failure, ischemia-reperfusion injury, metformin Citation Khinchin J, Rakoubian A, Romano V, Ryan T, Yarbro J, Kobayashi S and Liang Q (2026) Repurposing metformin for cardioprotection: mechanisms and therapeutic potential across cardiovascular pathologies