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The most consistently reported pathway involves VEGFR2 and the Akt-eNOS nitric oxide cascade

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Critical supporting codes that should accompany the E66 primary diagnosis include: Z68.30 through Z68.45 - BMI codes specifying the exact range (Z68.35 = BMI 35.0-35.9, Z68.41 = BMI 41.0-44.9, etc.) I10 - Essential hypertension (a qualifying comorbidity) E78.5 - Hyperlipidemia, unspecified (another qualifying comorbidity) G47.33 - Obstructive sleep apnea (a qualifying comorbidity) E11.9 - Type 2 diabetes (if present as comorbidity) Loading the claim with all applicable comorbidity codes significantly improves the chances of first-pass approval