However, at a constant concentration of GSH with varying concentrations of GSH, Lineweaver-Burk and Hofstee plots of initial velocity as function of glutathione concentration revealed apparent K m and Vm values: 27.62 M and 0.66 nmoles ml -1 min -1 respectively
Kagawa H, Javali A, Khoei HH, Sommer TM, Sestini G, Novatchkova M, Scholte Op Reimer Y, Castel G, Bruneau A, Maenhoudt N, Lammers J, Loubersac S, Freour T, Vankelecom H, David L, Rivron N (2022) Nature 601:600605
Nanomedicine in cancer therapy
The same vascular growth activity raises a biologically plausible concern: accelerating angiogenesis in a tissue that already harbors occult or established malignancy could support tumor growth