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Since INS-1E cells are rat-derived, we used the mRNA sequence encoding rat 2A -adrenergic receptor as a template to generate guide RNA (gRNA) to disrupt the promoter region of the Adra2a gene (gRNA sequence: 5-GCAGCCGGATGCCGGCAATA-3, positions 5776)

In vitro protective effect and antioxidant mechanism of resveratrol induced by dapsone hydroxylamine in human cells

Glutathione S -transferase M1, T1, and P1 polymorphisms as risk factors for renal cell carcinoma: a case-control study

Vitamin B12 (cobalamin) refers to a group of chemically-related cobalt-containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production, and regulation