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Nine patients had a mutated immunoglobulin heavy chain (IGHV) gene, which is associated with a favorable prognosis, and 2 had an unmutated gene

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Meanwhile, overall aging indicators were significantly improved: locomotor activity and endurance were enhanced, hair gloss increased, levels of aging-related inflammatory factors (such as TNF-, IL-6) decreased, and the average lifespan of mice was prolonged

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