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TB-500 human data is primarily from ophthalmic applications (RGN-259 and RGN-137, which use full-length Thymosin Beta-4, not the TB-500 fragment)

Chronic treatment with a melanocortin-4 receptor agonist causes weight loss and improves insulin sensitivity in diet-induced obese monkeys. J Clin Endocrinol Metab

Chronic inflammation, gut permeability ("leaky gut"), and metabolic dysfunction are common underlying factors in both autoimmune flares and long COVID symptom patterns, including brain fog, fatigue, and digestive issues