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Restoration of p53 function leads to tumour regression in vivo

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These studies have consistently reported biomarker responses such as inhibition of acetylcholinesterase (AChE) activity, altered ethoxyresorufin O-deethylase (EROD) and glutathione S-transferase (GST) levels, erythrocytic nuclear abnormalities, and histopathological lesions in gill and liver tissues (Pathiratne et al., 2010b

Campioni M, Santini D, Tonini G, Murace R, Dragonetti E, Spugnini EP, et al

These vesicles act as cell-free molecular carriers of microRNAs, growth factors, and signaling proteins capable of reprogramming fibrotic and ischemic tissue microenvironments [20, 21]