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[DOI] [PMC free article] [PubMed] [Google Scholar] 69.Griffith OW, Meister A: Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)

\Potentially Lower Risk: May carry a lower theoretical risk of abnormal cell growth compared to direct GH injections because it works within the body's natural feedback limits

It is expected to reach an ultimate value of US$0.85 Billion in the next five years

Injection site reactions remain present but predictable and manageable

Responsible for the hydrolysis of CysGly is the neuronal aminopeptidase N, as demonstrated by the ability of an inactivating specific antibody against aminopeptidase N to prevent the utilization of CysGly for neuronal GSH synthesis (Dringen et al