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Graphical Abstract Similar content being viewed by others Introduction The tight junction-connected, non-fenestrated brain capillary endothelial cells in cross-talk with the neighboring pericytes and astroglial endfeet create the dynamic anatomical and functional unit called as bloodbrain barrier (BBB) [1]

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Bacteriostatic water itself is not a controlled substance in the UK

However, such methods have been either unpractical and/or unsuccessful