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If you do notice any reaction at the injection site (such as warmth or a small lump), it can help to gently apply a cool compress

It has a molecular weight of approximately 403.9 Da in its free peptide form (or ~340.4 Da without the copper ion)

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In addition, once-daily administration of 1 mg oral hydroxocobalamine caused the studied children's levels of homocysteine to increase and their levels of methionine to decrease, while the reverse happened when hydroxocobalamine was given intramuscularly