Neurons in the hippocampus are particularly vulnerable to such damage due to their high metabolic activity and relatively low levels of endogenous antioxidants (Rego and Oliveira, 2003), where oxidised cellular components, such as lipids, proteins, and DNA, can disrupt normal cellular functions, impairing synaptic function and plasticity, which are essential for memory formation and retrieval (Singh et al., 2019)
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