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The presence of the specialized tripeptide KPV allows researchers to monitor the competitive downregulation of nuclear factor kappa B (NF-kB) and trace the inhibition of pro-inflammatory cytokines like tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) within inflamed intestinal or cutaneous tissues

Hebert SA, Ibrahim HN

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In the context of CI-AKI, the activation of mitophagy by BBR may counteract damaging effects via the reduction of ROS accumulation

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