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Meanwhile, maleimide will exhaust cellular GSH to further enhance the ROS generation

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Furthermore, NSCLC patients with durable clinical benefit post-ICB had significantly lower circulating IGF-1 and lower tumor IGF-1R than those with no durable benefit 19

[38] Ketoconazole can inhibit testosterone secretion at doses of 200-400 mg/day and can inhibit cortisol synthesis in doses of 400-600 mg/day