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Our results underscore that smoking cessation should remain the most effective way to reduce the risk of lung cancer development, but smoking reduction may be used as an adjusted strategy to reduce the risk of lung cancer in patients with COPD, particularly in those who have smoked less than 30 pack-years and are unable to quit smoking immediately

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Consider reaching out to a healthcare provider or addiction specialist if you experience severe depression or suicidal thoughts during withdrawal, have previously been unable to quit despite multiple attempts, have a co-occurring mental health condition such as anxiety or depression, or are using both nicotine and other substances simultaneously

Because they are used orally and involve swallowing tobacco juice, there is increased concern about the possibility of oral, esophageal and stomach cancers arising among long-term users