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In the normal state of cells, Nrf2 binds to kelch-like ECH-associated protein-1 (Keap1) to form a complex, which exists in the cytoplasm
Always consume the liquid within 24 hours after opening to maintain its effectiveness
Its biocompatibility, low cytotoxicity, and PEG-like stealth properties, combined with enhanced stability against hydrolysis and reduced crystallinity, make PEtOx ideal for drug delivery, tissue engineering, hydrogels, micelles, nanoparticles, and antifouling coatings [79]
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Nonetheless, further comprehensive studies are required to elucidate the potentially complex mechanisms through which lactylation regulates cell reprogramming
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