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Similarly, acute exposure to e-cigarette aerosol increased secretion of IL-8 by primary human alveolar type 2 cells [25, 33], increased mRNA for IL-6, TNF-, chemokine (C-X-C motif) ligand (CXCL)-8, monocyte chemoattractant protein-1 by primary human alveolar macrophages [26], increased release of endothelial microparticles in humans [35], increased IL-8 and IL-12A expression by human bronchial organoids and A549 cells [36] and increased production of IL-6 and IL-8 by primary human fibroblasts [28], primary human tracheobronchial epithelial cells [37, 38] and human monocyte-derived dendritic cells [39]

Copeland & Carney, 2003)

Still, not dying of lung cancer seemed like a major plus

Given the substantially higher rates of vaping within younger age cohorts, we also explored the relationships between vaping, cigarette consumption, and psychological distress by age