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-Glutamylcyclotransferase (GGCT) is a key enzyme catalyzing 5-oxoproline formation in the - glutamyl cycle

For instance, KG, also known as 2-oxoglutarate (2OG), is a co-substrate for KGDDs that include DNA and histone demethylases 2

Lower selenium urinary concentrations were reported in vegetarians and vegans in some studies [70,71,72,73] although other studies showed similar levels between plant-based diets and omnivorous diets [74]

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Furthermore, a significant increase in the protein expression of pS396-tau, pT231-tau, and pS202/205-tau and a decreased number of neurons in the hippocampus and prefrontal cortex were observed