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The Protein A affinity chromatography resin captures IgGs from various mammalian species with different affinities under physiological buffer conditions (pH 7.27.4), whereas other molecules and antibodies flow through

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Given the frequent occurrence of anxiety, depression, and other psychiatric conditions in individuals with ME/CFS, exploring alternatives to traditional psychotropic drugs is essential [88]

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Among the 4 patients who developed thyroid dysfunction in the Abs-negative group, two had a positive anti-thyroid antibody status at thyroid dysfunction onset (positive TgAb and TPOAb in one and positive TgAb in the other patient), suggesting the involvement of thyroid autoimmunity even in patients negative for anti-thyroid antibodies at baseline