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Relationship between IGF-I concentration and metabolic profile in children with growth hormone deficiency: The influence of childrens nutritional state as the ghrelin, leptin, adiponectin, and resistin serum concentrations

Ageing can be associated with the reduction of nutrient intake, known as anorexia of ageing, representing a physiological feature of old age associated with decreased energy expenditure and loss of muscle mass ( Reference Landi, Calvani and Tosato 35 )