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The concept of lipophilicity, often described qualitatively in terms of hydrophobic surface contribution, is relevant when evaluating reversed-phase chromatographic behaviour

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In addition to its involvement in synaptic plasticity and transmission, free ARA plays a crucial role in neuroinflammation through its conversion into various eicosanoids by cyclooxygenases, prostaglandin synthases, and lipoxygenases, the activities of which have been associated with neurodegenerative diseases (Esposito et al., 2008), ARA consumption could constitute a risk factor for AD in humans and should be considered in future preventive strategies

Buckley, Gillian J., Palmer, Guy H

Fernandes BS, et al