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Co-administration of iRGD with sorafenib-loaded iron-based metal-organic framework as a targeted ferroptosis agent for liver cancer therapy

The effect is dose-dependent and well documented

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To investigate whether these DMF-mediated alterations are related to the expression changes of DNA methylation modifiers, we determined the expression of DNA methyltransferases (DNMTs) and TET methylcytosine dioxygenases (TETs) in cultured Day 12 SCD erythroblasts