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Ethical approval The study was approved by the Ethics Committee of Peking Union Medical College Hospital (No

Despite the pharmacokinetic limitations, irregular adsorption and fast catabolism, the l-dopa became the standard oral pharmaceutical therapy of PD in the last fifty years [7]

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Taken together, the effects of alcohol, whether positive or negative, probably depend on the amount consumed [304], since increasing doses can accumulate within tissues and cause irreversible tissue damage, despite future efforts to abstain from alcohol