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doi: 10.2174/1570159x13666160502153022
(1) Omega-3 PUFAs (EPA/DHA) as core antidepressant components Deep-sea fish (e.g., salmon, mackerel) contain 23 g/100 g of EPA and DHA, which target two key pathways of depression: Inhibiting microglial activation: by inhibiting the NF-B/MAPK p38 signaling pathway and activating the neuronal BDNF-PI3K/AKT pathway, the process achieves a balance in microglial M1/M2 polarization and provides neuroprotection against neuroinflammation (313)
Del Pozo-Rodriguez, A
In healthy (normal blood pressure) rats, long-term administration of enalapril ( 41 , an angiotensin converting enzyme inhibitor) was associated with significant weight loss and a longer life span [185]
Scope & compliance: This is regulatory-status information, not medical or legal advice
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