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GHK-Cu also stimulates epidermal basal cells, markedly increasing integrins and p63 expression while promoting more cuboidal cell shapes indicative of enhanced stemness properties

Guidelines currently recommend organ-specific management of obesity-related complications

Many growth factors such as transforming growth factor (TGF)-, 2 platelet-derived growth factor (PDGF), 3 epidermal growth factor (EGF), 4 and fibroblast growth factor (FGF), 5 as well as interleukin (IL)-1 6 and tumor necrosis factor (TNF), 7 have been evaluated in a wide spectrum of in vivo and in vitro experiments to observe their effects on different elements included in the healing process