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A concentration range of 2-5% is generally effective for skin lightening purposes without causing irritation

doi: 10.1056/NEJM197803092981002 206 MooreGWSwiftLLRabinowitzDCroffordOBOatesJAStacpoolePW

Scleral inflammation is classified into episcleritis, which is the inflammation of the thin vascular connective tissue on the scleral surface, and scleritis, an inflammation of the scleral matrix layer arising from collagen fiber destruction and cellular infiltration by inflammatory factors [123]

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