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It then travels to the kidneys, where it converts to L-arginine , the direct precursor to nitric oxide (NO)

In this study, a robust hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS) method was developed and optimized for the comprehensive analysis of glutathione metabolism in cell samples without chemical derivatization

Nag S, Kar S, Mishra S, Stany B, Seelan A, Mohanto S, Kamaraj C, Subramaniyan V

2002, 283: R29-R45

NAC is also an antioxidant itself as a source of sulfhydryl groups in cells and scavenger of free radicals as it interacts with reactive oxygen species such as OH and H 2 O 2 60