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189 Moreover, prostate cancer (PCa) cell-derived lactate induces H3K18la in TAMs, inhibiting the activation and phagocytosis of PC cells, which ultimately promotes the occurrence of the PTEN/p53-deficient aggressive-variant PC
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Depletion of GSH is observed in patients with hepatitis virus, HIV, HSV-1, etc
Genetic predisposition plays a crucial role with genes such as ABCG5 and ABCG8 association with gallstone susceptibility [6, 7]