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doi: 10.1096/fj.03-0782fje

Patients frequently report an energy change in the first day or two, which is most plausibly B12 in deficient patients, and expectation in everyone else

[DOI] [PubMed] [Google Scholar] 61.Kobayashi-Hattori K, Mogi A, Matsumoto Y, Takita T

[1] Some compounders suggest adding B12 to tirzepatide formulations based on theoretical concerns about vitamin B12 absorption, though it's important to note that clinical evidence specifically linking tirzepatide to B12 deficiency is lacking