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In renal pathologies, sUA stimulates inherent renal cells, including endothelial cells, vascular smooth muscle cells, and renal tubular cells, to upregulate or secrete high mobility group protein 1 (HMGB1), inflammatory cytokines, and chemokines

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Glutathione is part of your bodys built-in antioxidant defense system that helps protect you from these free radicals

78 The NLRP3 inflammasome, part of the nucleotide-binding domain and leucine-rich repeat protein family complex, is essential in the development of numerous infections and inflammatory disorders

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