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In embryonic Drosophila , the activation of DUOX and subsequent H 2 O 2 production was shown to be triggered by wound-induced calcium (Ca 2+ ) flashes, where Ca 2+ binds to an EF hand Ca 2+ -binding motif of DUOX 72

Involvement of superoxide anion generation in the hypersensitive response of potato tuber tissues to infection with an incompatible race of Phytophthora infestans and to the hyphal wall components

Mueller S, Riedel HD, Stremmel W

This hypercoagulable state is sometimes called thrombophilia and is associated with severe illness and poor outcomes

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